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Erythema annulare centrifugum in Child
Other Resources UpToDate PubMed

Erythema annulare centrifugum in Child

Contributors: Vivian Wong MD, PhD, Belinda Tan MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed


Erythema annulare centrifugum (EAC) is characterized by circular or polycyclic lesions that may be superficial or deep. Individual lesions enlarge over days to months and subsequently resolve, but new lesions may continue to develop for weeks to years. They may be anywhere on the body, and usually several are present at once. EAC can occur at any age but tends to affect young or middle-aged adults. There is no sex or racial predilection.

Some believe there is an association with underlying infection (fungal, yeast, Pseudomonas aeruginosa, poxvirus, Epstein-Barr virus, mycobacteria, ascariasis), medications, malignancy (leukemia, Hodgkin lymphoma), blue cheese ingestion, or collagen vascular diseases.


L53.1 – Erythema annulare centrifugum

399914006 – Erythema annulare centrifugum

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Superficial lesions may be confused with:
  • Tinea corporis
  • Pityriasis rosea
Other considerations:
  • Erythema gyratum repens (faster moving)
  • Erythema migrans (marker of Lyme disease)
  • Annular Urticaria
  • Urticaria multiforme
  • Urticarial phase of Bullous pemphigoid
  • Erythema multiforme
  • Erythema marginatum (rheumatic fever)
  • Necrolytic migratory erythema (associated with Glucagonoma syndrome)
  • Psoriasis
  • Tumid lupus erythematosus
  • Granuloma annulare
  • Sarcoidosis
  • Cutaneous T-cell lymphoma

Best Tests

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Management Pearls

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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Last Reviewed:02/21/2018
Last Updated:09/30/2019
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Erythema annulare centrifugum in Child
A medical illustration showing key findings of Erythema annulare centrifugum : Scattered few, Annular configuration, Fine scaly plaques
Clinical image of Erythema annulare centrifugum - imageId=7644. Click to open in gallery.  caption: 'A close-up of two confluent annular and erythematous plaques with central collarettes of scale.'
A close-up of two confluent annular and erythematous plaques with central collarettes of scale.
Copyright © 2024 VisualDx®. All rights reserved.