Exogenous steroid abuse
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Synopsis

Exogenous steroid abuse is a cause of cardiovascular disease and virilization, typically in young males. Anabolic and androgenic steroids are abused by amateur and professional athletes alike. Exogenous steroid use can cause myocardial infarction, stroke, hyperlipidemia, acne, gynecomastia, gingival enlargement, testicular atrophy, and behavioral changes. Exogenous steroids commonly abused include testosterone esters and synthetic anabolic steroids such as nandrolone and stanozolol. Hypogonadism and depression may develop with abrupt discontinuation of steroids. Most effects of steroid abuse reverse after discontinuation, but balding, voice changes, and breast development are not always reversible.
Codes
ICD10CM:
F55.3 – Abuse of steroids or hormones
SNOMEDCT:
231458000 – Abuse of steroids
F55.3 – Abuse of steroids or hormones
SNOMEDCT:
231458000 – Abuse of steroids
Differential Diagnosis & Pitfalls
- Endocrine disorders (eg, adrenal hyperplasia, pituitary disorders, acromegaly)
- Chromosomal abnormalities (eg, Klinefelter syndrome)
- Drug side effects (eg, chemotherapies for hypogonadism, risperidone for gynecomastia, amphetamines for behavioral changes)
- Malignancy (particularly hormone-secreting tumors of the testes, ovaries, adrenals)
- Hemochromatosis
- Hypothyroidism / hyperthyroidism
- Psychiatric disorder (eg, body dysmorphic disorder)
- Polycystic ovary syndrome
Best Tests
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Drug Reaction Data
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.
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References
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Last Updated:06/20/2017