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Fordyce angiokeratoma of scrotum
See also in: Anogenital
Other Resources UpToDate PubMed

Fordyce angiokeratoma of scrotum

See also in: Anogenital
Contributors: Rajini Murthy MD, Benjamin K. Fisher MD, Lowell A. Goldsmith MD, MPH, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Angiokeratomas of the scrotum (Fordyce angiokeratomas) are benign, often asymptomatic, 2-5 mm, warty or smooth-topped, red-to-violaceous papules composed of dilated dermal capillaries. The pathophysiology is unknown, but it is speculated that they may be caused by increased venous pressure due to their occasional association with vascular conditions such as varicoceles. The lesions may bleed spontaneously or with slight trauma, which is often distressing to patients.

The condition is more common in men. However, angiokeratomas may also be seen on the inner thighs, lower abdomen, and on the vulva in women (angiokeratoma of vulva). Prevalence data indicates that the condition is more common in individuals of Northern European and Japanese descent, and that incidence increases with advancing age.

Codes

ICD10CM:
D29.4 – Benign neoplasm of scrotum

SNOMEDCT:
735082004 – Fordyce angiokeratoma of scrotum

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

  • Genital wart
  • Cherry hemangioma
  • Bowenoid papulosis
  • Lymphangioma circumscriptum
  • Glomangiomas
  • Angiokeratoma corporis diffusum (see Fabry disease) – Consider this diagnosis in more widespread cases that involve extragenital skin. Macules and papules of angiokeratoma corporis diffusum are smaller and appear at an earlier age.
  • Hereditary hemorrhagic telangiectasia
  • Common acquired nevus
  • Melanoma

Best Tests

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Management Pearls

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Therapy

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References

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Last Reviewed:08/03/2021
Last Updated:08/08/2021
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Fordyce angiokeratoma of scrotum
See also in: Anogenital
A medical illustration showing key findings of Fordyce angiokeratoma of scrotum : Smooth papules
Clinical image of Fordyce angiokeratoma of scrotum - imageId=73207. Click to open in gallery.  caption: 'A close-up of multiple maroon and dark purple scrotal papules of varying sizes.'
A close-up of multiple maroon and dark purple scrotal papules of varying sizes.
Copyright © 2024 VisualDx®. All rights reserved.