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Gastric ulcer
Other Resources UpToDate PubMed

Gastric ulcer

Contributors: Sanah Ali, Desiree Rivera-Nieves MD, Khaled Bittar MD, Nishant H. Patel MD, Paritosh Prasad MD
Other Resources UpToDate PubMed


Gastric ulcer (stomach ulcer), a common form of peptic ulcer disease, is an ulceration occurring in the lining of the gastric mucosal membrane caused by stomach acid damage to the digestive tract. Prevalence is similar across men and women, with a slightly higher incidence in men. There is an increase in incidence and mortality with age.

Seventy percent of peptic ulcers are asymptomatic, and 60% of peptic ulcers heal spontaneously.

Gastric ulcers can be associated with Helicobacter pylori infection or ingestion of NSAIDs. Other risk factors include smoking, excessive alcohol consumption, steroids, and high-salt diet. Less common etiologies include ischemia in the setting of severe burns (Curling ulcer) and uncontrolled activation of parietal cells due to vagal stimulation via elevated intracranial pressure (Cushing ulcer).

Gastric ulcers may lead to hemorrhage, perforation, infection, or scar tissue if left untreated.


K25.9 – Gastric ulcer, unspecified as acute or chronic, without hemorrhage or perforation

397825006 – Gastric ulcer

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Last Reviewed:05/14/2017
Last Updated:05/18/2020
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Gastric ulcer
A medical illustration showing key findings of Gastric ulcer : Abdominal pain, Nausea, Vomiting, Anorexia
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