Gastrointestinal stromal tumor
Alerts and Notices
Synopsis

Clinical manifestations include nonspecific symptoms such as early satiety and bloating. Often, GISTs are discovered on imaging performed for another purpose. GISTs may remain asymptomatic unless they ulcerate, bleed, or grow large enough to cause mechanical obstruction. Sites of metastases include the liver and peritoneum; lymph node metastases are not common.
Related topic: Extra-gastrointestinal stromal tumor
Codes
ICD10CM:D48.1 – Neoplasm of uncertain behavior of connective and other soft tissue
SNOMEDCT:
420120006 – Gastrointestinal stromal tumor
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Malignancy (particularly stomach, small intestine, pancreas, colon)
- Solitary fibrous tumor
- Leiomyoma
- Desmoid tumor
- Lipoma
- Adenomatous polyps
- Small bowel obstruction
- Adhesions
- Inflammatory bowel disease (eg, Crohn disease, ulcerative colitis)
- Peptic ulcer disease
Best Tests
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Management Pearls
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Therapy
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References
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Last Reviewed:12/20/2017
Last Updated:01/16/2022
Last Updated:01/16/2022