Contents

SynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferences

View all Images (12)

Giant cell tumor of tendon sheath - Nail and Distal Digit
See also in: Overview
Print Captions
Other Resources UpToDate PubMed

Giant cell tumor of tendon sheath - Nail and Distal Digit

See also in: Overview
Print Images (12)
Contributors: Shari Lipner MD, PhD, Belinda Tan MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed

Alerts and Notices

Synopsis

Giant cell tumor of tendon sheath : Fingers, Index finger, Smooth nodule, Solitary nail or digit, Hands
Giant cell tumor of the tendon sheath (GCTTS) is a soft-tissue tumor most commonly found attached to the flexor surfaces of the tendons of the fingers, hands, and wrists. In these locations, the second and third digits are most often involved, particularly near the distal interphalangeal joint. The second most frequent site of occurrence is the ankle-foot region, with toe involvement rare. Individual lesions tend to range from 1-3 cm in diameter and are persistent. GCTTS may occur at any age but is most common in the third to fifth decades. These tumors are typically less frequent in children. The majority of GCTTS present with a history of a gradually enlarging soft-tissue swelling or firm, palpable mass. The tumor may interfere with normal functioning of the joint.

GCTTS has been classified into 2 types. The nodular type is often localized to the hands, has a pseudocapsule, and has a slight predilection for females. The diffuse type is often localized to larger joints and presents with multicentric tumors or satellite lesions without capsules. The diffuse type tends to recur after excision and affects both sexes equally.

GCTTS is thought to result from a reactive inflammatory process. Other hypotheses posit that it arises from the synovial membrane, sesamoid bones, or primitive mesenchymal cells.

Almost all cases are benign, but malignant degeneration has rarely been reported.

Codes

ICD10CM:
D48.1 – Neoplasm of uncertain behavior of connective and other soft tissue

SNOMEDCT:
95413004 – Nodular tenosynovitis

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Reviewed:02/25/2019
Last Updated:03/05/2019
Copyright © 2023 VisualDx®. All rights reserved.
Giant cell tumor of tendon sheath - Nail and Distal Digit
See also in: Overview
Captions Print   View all Images (12)
(with subscription)
A medical illustration showing key findings of Giant cell tumor of tendon sheath : Fingers, Index finger, Smooth nodule, Solitary nail or digit, Hands
Clinical image of Giant cell tumor of tendon sheath - imageId=2948899. Click to open in gallery. caption: 'A smooth reddish and yellowish nodule with overlying telangiectasias on the distal finger.'
A smooth reddish and yellowish nodule with overlying telangiectasias on the distal finger.

+10 More images of Giant cell tumor of tendon sheath with subscription

Copyright © 2023 VisualDx®. All rights reserved.