ContentsSynopsisCodesDifferential Diagnosis & PitfallsBest TestsReferences
Gonadoblastoma
Other Resources UpToDate PubMed

Gonadoblastoma

Contributors: Michael W. Winter MD, Benjamin L. Mazer MD, MBA
Other Resources UpToDate PubMed

Synopsis

Rare benign tumor consisting of a combination of mixed germ cells and sex cord stroma derivatives (Sertoli-like and granulosa-like cells), commonly arising in dysgenetic gonads. Occurs in males and phenotypic females with a Y chromosome. Tumors may produce excess testosterone or estrogen, causing findings such as abnormal genitalia, amenorrhea, virilization, and pelvic mass. Unilateral or bilateral. Most frequently diagnosed before the third decade. Lesion sizes vary from 1 mm up to 20 cm. May calcify. Associated with abnormal karyotype. Patients are at risk for developing a malignant germ cell tumor.

Codes

ICD10CM:
D39.10 – Neoplasm of uncertain behavior of unspecified ovary
D40.10 – Neoplasm of uncertain behavior of unspecified testis

SNOMEDCT:
74751003 – Gonadoblastoma

Differential Diagnosis & Pitfalls

Best Tests

Subscription Required

References

Subscription Required

Last Updated:05/27/2016
Copyright © 2021 VisualDx®. All rights reserved.
Gonadoblastoma
Print  
Gonadoblastoma : Amenorrhea, Pelvic mass, Virilization
Copyright © 2021 VisualDx®. All rights reserved.