ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferencesView all Images (7)
Granular cell myoblastoma of vulva - Anogenital in
Other Resources UpToDate PubMed

Granular cell myoblastoma of vulva - Anogenital in

Contributors: Kaylee Underkofler MD, MPH, Mitchell Linder MD
Other Resources UpToDate PubMed

Synopsis

Granular cell myoblastoma is a slow-growing submucosal tumor derived from the nerve sheath. It is located on the vulva in approximately 10% of cases, although it is more commonly seen in the nasopharyngeal area, particularly on the tongue. It can be multifocal.

Granular cell myoblastoma is seen most commonly in adults, but it presents in children as well. The median age at diagnosis is between 30 and 50 years. It is more common among Black women.

The majority of cases of granular cell myoblastoma are benign, but 2% are found to be malignant. They can recur; thus, surveillance is warranted.

Related topic: granular cell tumor

Codes

ICD10CM:
D17.30 – Benign lipomatous neoplasm of skin and subcutaneous tissue of unspecified sites

SNOMEDCT:
404035005 – Granular cell myoblastoma

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

  • Associated pseudoepitheliomatous hyperplasia on a mucocutaneous surface can be misinterpreted as cancer. Careful slide review is recommended.
  • Sebaceous cyst – Smooth, encapsulated subdermal mass filled with purulent fluid. Ultrasound will reveal a fluid-filled mass rather than a solid soft-tissue mass consistent with granular cell myoblastoma.
  • Lipoma – Soft subcutaneous mass comprised of adipose tissue. Excision and pathology review will differentiate from granular cell myoblastoma.

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Reviewed:01/04/2021
Last Updated:01/04/2021
Copyright © 2021 VisualDx®. All rights reserved.
Granular cell myoblastoma of vulva - Anogenital in
Granular cell myoblastoma of vulva : Female genital, Labia majora, Smooth nodule, Tumor
Clinical image of Granular cell myoblastoma of vulva
A close-up of a smooth pinkish nodule.
Copyright © 2021 VisualDx®. All rights reserved.