Granuloma annulare in Adult
Some reports in the literature have suggested that GA is associated with certain triggers or systemic diseases, most commonly diabetes mellitus; other diseases that may be associated include thyroid disease, dyslipidemia, malignancy, and infections.
There are 3 principal variants of GA: localized (75% of cases), generalized (or disseminated), and subcutaneous (also known as pseudo-rheumatoid nodules). Patch GA is a variant of localized GA in which the plaques are extremely thin and barely palpable. A fourth type – perforating GA – refers to rare lesions that demonstrate histologic evidence of transepidermal extrusion of degraded collagen. Actinic granuloma presents with similar lesions and is thought by some to represent GA occurring in sun-damaged skin. Palmoplantar GA is a rare variant favoring the palms.
L92.0 – Granuloma annulare
65508009 – Granuloma annulare
- GA is often mistaken for dermatophyte infection (tinea corporis, or "ringworm"). The presence of scale in dermatophyte infection should allow the distinction.
- Subcutaneous forms of GA may be confused with rheumatoid nodules.
- Interstitial granulomatous dermatitis
- Palisaded neutrophilic granulomatous dermatitis
- Perforating collagenosis
- Elastosis perforans serpiginosa
- Erythema annulare centrifugum
- Lichen planus (especially the annular variant) – Usually pruritic.
- Leprosy – Anesthetic lesions in endemic countries.
- Erythema elevatum diutinum – Over extensors, pruritic.
- Necrobiosis lipoidica – Atrophic plaques.
- Erythema migrans (Lyme disease) – Slow growing, more erythematous.
- Erythema gyratum repens
- Sweet syndrome
- Subacute cutaneous lupus erythematosus
- Annular elastolytic giant cell granuloma
- Mycosis fungoides