Granuloma gluteale infantum arises as a complication of a preceding inflammatory skin condition treated with a variety of agents, but particularly after the use of topical corticosteroids. Postulated causes include topical halogenated corticosteroids, diapering items, candidal infection, or skin contact with urine and feces.
The condition is rare, occurring more often in male infants between 3 and 9 months of age. Lesions persist for 3-6 weeks and spontaneously regress with good diaper hygiene. Pain, secondary infection, and scarring are potential complications.
Related topic: Granuloma gluteale adultorum
Granuloma gluteale infantum
See also in: AnogenitalAlerts and Notices
Synopsis
Codes
ICD10CM:
L22 – Diaper dermatitis
SNOMEDCT:
240710003 – Granuloma gluteale infantum
L22 – Diaper dermatitis
SNOMEDCT:
240710003 – Granuloma gluteale infantum
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Candidiasis – Usually also in the intertriginous spaces.
- Irritant or contact dermatitis – More diffuse, less nodular.
- Langerhans cell histiocytosis – In histiocytosis X, a scaly seborrheic, eczematoid, sometimes purpuric rash involving the scalp, ear canals, abdomen, and intertriginous areas of the neck and face; usually a solitary lesion in eosinophilic granuloma.
- Urticaria pigmentosa – Results in urtication with firm stroking.
- Mastocytoma – Results in urtication with firm stroking.
- Juvenile xanthogranuloma – Usually a solitary lesion of the head and neck.
- Cutaneous T-cell lymphoma
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Management Pearls
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Therapy
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Drug Reaction Data
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.
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References
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Last Updated:05/06/2019
Granuloma gluteale infantum
See also in: Anogenital