Hepatoblastoma
Alerts and Notices
Synopsis
Hepatoblastomas present as a rapidly growing singular well-circumscribed solid mass. They are more common in the right hepatic lobe. Due to rapid growth, rupture and hemorrhage are potentially deadly complications if unrecognized. Microscopically, these tumors are composed of embryonal and fetal hepatic elements. Prognosis is based on histologic type, with well-differentiated pure tumors having the best prognosis and poorly differentiated small cell tumors having the worst prognosis.
Symptoms include abdominal swelling, abdominal pain, vomiting, poor feeding or feeding intolerance, weight loss, anorexia, and irritability. Serum alpha fetoprotein (AFP) is elevated in 80%-90% of patients. Tumor rupture may present with vomiting, peritonitis, and severe anemia.
Codes
ICD10CM:C22.2 – Hepatoblastoma
SNOMEDCT:
109843000 – Hepatoblastoma
Look For
Subscription Required
Diagnostic Pearls
Subscription Required
Differential Diagnosis & Pitfalls
- Hepatocellular carcinoma
- Angiosarcoma
- Hepatocellular adenoma
- Sarcoma
- Liposarcoma
- Lymphoma
- Rhabdomyosarcoma
- Focal nodular hyperplasia
- Metastatic disease
Best Tests
Subscription Required
Management Pearls
Subscription Required
Therapy
Subscription Required
References
Subscription Required
Last Reviewed:05/06/2018
Last Updated:06/26/2022
Last Updated:06/26/2022