Herpes simplex virus in Infant/Neonate
Characteristic skin lesions are vesicles, pustules, crusts, or erosions. Rarely there can be coinfection of the skin with Staphylococcal aureus and HSV together.
Other symptoms of primary HSV infection in an infant include feeding problems, fever, and/or lethargy. In infants with atopic dermatitis, HSV can spread widely (eczema herpeticum).
See neonatal herpes for discussion of perinatal infection.
B00.1 – Herpesviral vesicular dermatitis
88594005 – Herpes simplex
Differential Diagnosis & Pitfalls
- Acropustulosis of infancy
- Congenital self-healing histiocytosis
- Molluscum contagiosum – Lesions are usually not painful, are slow to evolve, and are rarely grouped.
- Fixed drug eruption
- Herpes zoster
- Hand, foot, and mouth disease
- Contact dermatitis, allergic or irritant