Codes

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

• Cytomegalovirus infection – Timing of onset is typically 4-6 weeks posttransplant rather than years after transplant.
• Herpes zoster or herpes simplex virus reactivation – Characteristic painful lesions are distinct from the hyperkeratotic lesions observed in HPyV9 infection.
• Pneumocystis jirovecii infection – This diagnosis is established with bronchoalveolar lavage (BAL).
• Cutaneous lymphoproliferative disorders (eg, Epstein-Barr virus infection)
• Disseminated fungal infections (eg, Candida, cryptococcosis, histoplasmosis) – Diagnosis is established with urine culture or cerebrospinal fluid culture.
• Pruritic and dyskeratotic dermatosis
• Hypertrophic lichen planus
• Acquired perforating disease
• Eruptive keratoacanthomas
• Trichodysplasia spinulosa
• Lichenoid drug eruption
• Acrokeratosis paraneoplastica

Best Tests

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Management Pearls

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Therapy

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References

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