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Hyperglobulinemic purpura of Waldenström in All Ages
Other Resources UpToDate PubMed

Hyperglobulinemic purpura of Waldenström in All Ages

Other Resources UpToDate PubMed

Synopsis

A rare chronic disorder characterized by recurrent crops of nonthrombocytopenic petechiae and purpura on the dependent areas of the body, polyclonal hypergammaglobulinemia, and elevated ESR. This condition most commonly affects young to middle-aged females (late teens to 40s) but can be seen in children. It is classified as primary (idiopathic) or secondary to an underlying disease. The onset of hypergammaglobulinemic purpura often precedes the underlying disease by many years. The petechiae and purpura are frequently exacerbated by prolonged periods of standing, wearing tight clothing, alcohol intake, and exercise. Cases in pregnant patients have potential increased risk of poor maternal / fetal outcome.

Codes

ICD10CM:
D89.0 – Polyclonal hypergammaglobulinemia

SNOMEDCT:
190809001 – Waldenstrom hypergammaglobulinemic purpura

References

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Last Updated:12/16/2020
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Hyperglobulinemic purpura of Waldenström in All Ages
A medical illustration showing key findings of Hyperglobulinemic purpura of Waldenström : Hypergammaglobulinemia, Petechiae, ESR elevated, La positive, Ro positive, Lower legs
Clinical image of Hyperglobulinemic purpura of Waldenström - imageId=5144640. Click to open in gallery.  caption: 'Purpuric macules and papules around the ankle.'
Purpuric macules and papules around the ankle.
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