Juvenile gangrenous vasculitis (JGV) of the scrotum is a rare cause of sudden-onset scrotal ulceration that typically follows a prodrome of fever and pharyngitis or tonsillitis.

Fewer than 30 reports in the literature exist to date. While most reported patients were in their third decade, age range has varied between 15 and 45 years. Patients report scrotal itching, stinging, burning, or pain, which can precede or coincide with lesion presence. Patients are typically in good general health with no predisposing medical factors.

The etiology is unknown, but a number of contemporary authors believe JGV to be the male counterpart of Lipschutz ulcer. In most cases, no underlying infection can be identified; however, one case of coexisting streptococcal tonsillitis and one of acute Epstein-Barr virus infection have been reported.

JGV is self-limited, and complete resolution with mild atrophic scarring at affected sites is usually seen within 2-3 weeks.