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Emergency: requires immediate attention
Kawasaki disease - Anogenital in
See also in: Overview,External and Internal Eye,Oral Mucosal Lesion
Other Resources UpToDate PubMed
Emergency: requires immediate attention

Kawasaki disease - Anogenital in

See also in: Overview,External and Internal Eye,Oral Mucosal Lesion
Contributors: Tyler Werbel MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Kawasaki disease (KD), or mucocutaneous lymph node syndrome, is a self-limited, multisystem vasculitis that affects infants and children. The disease occurs primarily in children under the age of 6. It is classically characterized by fever lasting at least 5 days (usually longer) plus 4 of the 5 following criteria:
  • Conjunctival injection without exudate
  • Red lesions of the mouth or pharynx
  • Acute hand and foot edema followed by peeling
  • Polymorphous cutaneous eruption
  • Lymphadenopathy (usually cervical)
KD often presents with significant perineal erythema and subsequent desquamation over 2 days before development of diagnostic features of the disease. Careful evaluation and close follow-up is necessary for identification of other subtle clinical features suggestive of KD.

The most significant and potentially life-threatening complications are cardiovascular. Pericarditis, myocarditis, coronary arteritis, and endocarditis leading to arrhythmias can occur as early as 7 days from the onset of fever.

A multisystem inflammatory syndrome potentially linked to COVID-19 has been reported in children and young adults; clinical features include Kawasaki-like and toxic shock syndrome-like presentations.

Childhood sexual abuse is a problem of epidemic proportions affecting children of all ages and economic and cultural backgrounds. A variety of dermatologic conditions causing erythema of the perineum, including KD, should be considered when sexual abuse is suspected. Although awareness is increasing, it is often challenging to differentiate findings attributable to child abuse from those of other benign anogenital skin conditions.

For more information on Kawasaki disease, see OMIM.

Codes

ICD10CM:
M30.3 – Mucocutaneous lymph node syndrome [Kawasaki]

SNOMEDCT:
75053002 – Kawasaki disease

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Last Reviewed:08/08/2018
Last Updated:05/28/2020
Copyright © 2021 VisualDx®. All rights reserved.
Emergency: requires immediate attention
Kawasaki disease - Anogenital in
See also in: Overview,External and Internal Eye,Oral Mucosal Lesion
Kawasaki disease : Abdominal pain, Cervical lymphadenopathy, Diarrhea, Fever, Vomiting, Rash, Hand edema, Heart murmur, Irritability, Conjunctival injection, Strawberry tongue
Clinical image of Kawasaki disease
Erosions and hemorrhagic crusting on the lips.
Copyright © 2021 VisualDx®. All rights reserved.