Keloid in Adult
Keloids are most frequent in individuals of African descent and those of Mediterranean ancestry, but they can appear in any race or ethnicity. People with darker skin phototypes have a significantly higher tendency to form keloids, with an incidence as high as 16% in black Africans. There is likely a genetic basis for the tendency to develop keloids.
A distinction should be made between a keloid and a hypertrophic scar. All trauma that involves the dermis will heal with a scar; however, in certain individuals, the scar is much larger and thicker than what is considered normal. These lesions are termed hypertrophic scars. In contrast to keloids, hypertrophic scars are always preceded by trauma and are always confined to the margin of the wound. Hypertrophic scars also appear immediately after trauma and show a tendency to gradually regress, whereas keloids can be delayed in appearance and are thought to very rarely spontaneously resolve.
For more information, see OMIM.
L91.0 – Hypertrophic scar
33659008 – Keloid scar
- Hypertrophic scars – See also scar.
- Sarcoidosis – Can localize in scars and form nodules clinically similar to keloids.
- Foreign body reaction – Should be associated with a history of trauma to the site.
- Lobomycosis (keloidal blastomycosis) – Infection with Lacazia loboi.
- Dermatofibrosarcoma protuberans
- Xanthoma disseminatum (sclerotic form)
- Leukemia cutis