ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferencesView all Images (8)
Keratolysis exfoliativa
Print
Other Resources UpToDate PubMed

Keratolysis exfoliativa

Print Images (8)
Contributors: Lauren Croda, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Keratolysis exfoliativa (KE), also known as dyshidrosis lamellosa sicca, lamellar dyshidrosis, or recurrent focal palmar peeling, is a common palmoplantar blistering disorder of unknown pathogenesis. The notion that KE represents a mild form of dyshidrotic eczema has been challenged by a recent study of over twenty patients that showed the lack of eczematous features on histopathology.

In KE, annuli of erythema progress to air-filled superficial bullae that rupture to leave fine, expanding collarettes of scale. Bullae may coalesce and lead to desquamation of the entire volar surface; dorsal surfaces are less commonly involved.

While generally asymptomatic, KE can cause a mild, initial burning or tingling sensation and pain upon blister rupture. Chronically, thinning of the skin can cause local sensitivity. Involved surfaces are often associated with hyperhidrosis. Blistering is exacerbated by friction and moist, warm environments.

Codes

ICD10CM:
L26 – Exfoliative dermatitis

SNOMEDCT:
239065004 – Keratolysis exfoliativa

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Other causes of palmoplantar blistering dermatitis:

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Updated: 04/04/2018
Copyright © 2019 VisualDx®. All rights reserved.
Keratolysis exfoliativa
Print 8 Images
View all Images (8)
(with subscription)
Keratolysis exfoliativa : Desquamation, Erythema, Flaccid bullae, Hands and/or feet, Palms and soles, Symmetric extremities
Copyright © 2019 VisualDx®. All rights reserved.