Large cell acanthoma
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Synopsis

The etiology is unknown but thought to be related to extensive ultraviolet (UV) exposure. Analysis of clinical, histologic, and immunohistochemical properties suggests that the large cell acanthoma represents a reaction pattern evolving from a solar lentigo.
Codes
ICD10CM:D23.9 – Other benign neoplasm of skin, unspecified
SNOMEDCT:
733894009 – Large cell acanthoma
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Solar lentigo
- Lichen planus-like keratosis
- Clear cell acanthoma
- Pigmented actinic keratosis
- Pigmented seborrheic keratosis
- Squamous cell carcinoma in situ (Bowen disease)
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References
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Last Reviewed:10/19/2020
Last Updated:11/15/2020
Last Updated:11/15/2020