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Leiner disease in Child
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Leiner disease in Child

Contributors: Craig N. Burkhart MD, Dean Morrell MD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed

Synopsis

Leiner disease is a clinical phenotype marked by the triad of noncongenital or acquired erythroderma, diarrhea, and failure to thrive. Leiner disease may not represent a distinct clinical entity because infants with the clinical phenotype have eventually been diagnosed with various other conditions, including congenital immunodeficiencies, Netherton syndrome, Omenn syndrome, and eosinophilic gastroenteritis. Affected infants develop an acquired generalized desquamative dermatitis within the first few weeks of life. They also suffer from diarrhea, weight loss, and failure to thrive.

Codes

ICD10CM:
L21.1 – Seborrheic infantile dermatitis

SNOMEDCT:
7297005 – Leiner's disease

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Last Updated:01/18/2022
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Leiner disease in Child
Leiner disease : Diarrhea, Desquamation, Erythroderma, Failure to thrive
Clinical image of Leiner disease
Diffuse erythema and overlying flaky scale on the face and ear.
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