Lens subluxation or dislocation - External and Internal Eye
These patients become progressively myopic, often with large astigmatism and decreased vision. Patients may also complain of monocular diplopia and are at risk of developing amblyopia, glaucoma, and retinal detachment.
Ectopia lentis can be inherited as an isolated condition, usually autosomal dominant (simple ectopia lentis).
More commonly, lens displacement is associated with systemic syndromes, such as Marfan syndrome, homocystinuria, and Weill-Marchesani syndrome. It can also be associated with other ocular disorders such as aniridia, pseudoexfoliation syndrome, and congenital glaucoma. Other less common conditions associated with ectopia lentis include Ehlers-Danlos syndrome, sulfite oxidase deficiency, hyperlysinemia, congenital syphilis, Apert's disease, ectopia lentis et pupillae, spherophakia, iris coloboma, retinitis pigmentosa, and Reiger syndrome.
The most common cause of acquired lens displacement is trauma.
H27.119 – Subluxation of lens, unspecified eye
65814009 – Subluxation of lens
Differential Diagnosis & Pitfalls