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Lentigo maligna melanoma
Other Resources UpToDate PubMed

Lentigo maligna melanoma

Contributors: Jeffrey M. Cohen MD, William M. Lin MD, Susan Burgin MD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed

Synopsis

Lentigo maligna melanoma is a subtype of melanoma that develops when a lentigo maligna (a subtype of melanoma in situ) enters vertical growth phase and invades into the dermis. It is a tumor that may grow slightly above the surface of the skin and may be prone to bleeding. This cancer generally occurs 5-20 years after the lentigo maligna first develops. It is most frequently seen on sun-damaged skin (usually on the face) in individuals aged 60 or older.

Lentigo maligna melanoma is associated with nonmelanoma skin cancers, light skin, Werner syndrome, oculocutaneous albinism, and xeroderma pigmentosa.

Codes

ICD10CM:
C43.9 – Malignant melanoma of skin, unspecified

SNOMEDCT:
302837001 – Lentigo maligna melanoma

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

  • Solar lentigo
  • Lentigo maligna
  • Common acquired nevus
  • Melasma
  • Seborrheic keratosis
  • Pigmented basal cell carcinoma
  • Pigmented Actinic keratosis
  • Pigmented Squamous cell carcinoma in situ (Bowen disease)

Best Tests

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Management Pearls

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Therapy

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References

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Last Reviewed:01/02/2019
Last Updated:01/02/2019
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Patient Information for Lentigo maligna melanoma
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Lentigo maligna melanoma
A medical illustration showing key findings of Lentigo maligna melanoma : Face, Irregular configuration
Clinical image of Lentigo maligna melanoma - imageId=107337. Click to open in gallery.  caption: 'A variegated brown, violaceous, and blackish plaque on the helix.'
A variegated brown, violaceous, and blackish plaque on the helix.
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