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Libman-Sacks endocarditis
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Libman-Sacks endocarditis

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Contributors: Benjamin L. Mazer MD, MBA, Ryan Hoefen MD, PhD
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Synopsis

A noninfective cardiac valve disease seen in patients with systemic lupus erythematosus (SLE). Vegetations are composed primarily of inflammatory cells and fibrin clots. Endocarditis is caused by autoimmunity against a cardiac valve with concurrent hypercoagulability. Both mechanisms are usually attributable to antiphospholipid antibodies. Often asymptomatic, but may be discovered after a cardioembolism causes ischemic injury, such as stroke. Libman-Sacks endocarditis nearly always occurs on the mitral or aortic valves. It may sometimes cause valve dysfunction.

Treatment includes anticoagulation, immunosuppression for active SLE, and valve replacement in cases complicated by severe dysfunction.

Codes

ICD10CM:
M32.11 – Endocarditis in systemic lupus erythematosus

SNOMEDCT:
54072008  –  Nonbacterial verrucal endocardiosis

Differential Diagnosis & Pitfalls

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Last Updated: 07/13/2016
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Libman-Sacks endocarditis
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Libman-Sacks endocarditis : Exertional dyspnea, Heart murmur, Dyspnea, Asthenia
Copyright © 2019 VisualDx®. All rights reserved.