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Lichen sclerosus - Anogenital in
See also in: Overview,External and Internal Eye
Other Resources UpToDate PubMed

Lichen sclerosus - Anogenital in

See also in: Overview,External and Internal Eye
Contributors: Sabrina Nurmohamed MD, Belinda Tan MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Lichen sclerosus (LS) is a chronic scarring dermatosis of unknown etiology affecting individuals of all races. Lesions occur mostly on the genitalia, perineum, or perianal skin, but can appear anywhere.

LS presents as whitish plaques on the glans penis, prepuce, and shaft, frequently with subepidermal hemorrhages. If the glans penis and/or foreskin become involved, causing the tissues to shrink, the condition is called balanitis xerotica obliterans. The urethral meatus may also be involved. Although these lesions are mostly asymptomatic, there may be pruritus, burning on urination, meatal stenosis with difficulty voiding, phimosis, painful erections, diminished sensation of the glans, and sexual dysfunction.

Squamous cell carcinoma can arise in chronic, untreated genital lesions.

Codes

ICD10CM:
L90.0 – Lichen sclerosus et atrophicus

SNOMEDCT:
25674000 – Lichen sclerosus et atrophicus

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed:03/08/2017
Last Updated:05/06/2019
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Lichen sclerosus - Anogenital in
See also in: Overview,External and Internal Eye
Lichen sclerosus : Eyelids, Glans of penis, Labia majora, Smooth plaque, White color, Inguinal region, Pruritus, Skin atrophy, Hardened skin
Clinical image of Lichen sclerosus
A shiny white plaque in the intergluteal fold.
Copyright © 2022 VisualDx®. All rights reserved.