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Lichen sclerosus - Anogenital in
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Lichen sclerosus - Anogenital in

See also in: Overview,External and Internal Eye
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Contributors: Kudakwashe K. Maloney MD, MPhil, Belinda Tan MD, PhD, David Foster MD, Mary Gail Mercurio MD, Lynne Margesson MD
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Synopsis

Lichen sclerosus (LS) is the most common chronic vulvar condition. It is characterized by vulvar hypopigmentation and scarring with loss of normal architecture. Onset is typically 35-45 years of age, but it can be seen in children.

The main symptom is pruritus and at times this can be incapacitating, interfering with daily activity and sleep. Dyspareunia and urinary retention may occur. It can also be asymptomatic, just with scarring and hypopigmentation.

Squamous cell carcinoma can occur within LS genital lesions.

For more information, see OMIM.

Codes

ICD10CM:
L90.0 – Lichen sclerosus et atrophicus

SNOMEDCT:
25674000 – Lichen Sclerosus et Atrophicus

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated: 05/07/2019
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Lichen sclerosus - Anogenital in
See also in: Overview,External and Internal Eye
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Lichen sclerosus : Eyelids, Glans of penis, Labia majora, Smooth plaque, White color, Inguinal region, Skin atrophy, Hardened skin
Clinical image of Lichen sclerosus
A shiny white plaque in the intergluteal fold.
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