Lichen sclerosus - Anogenital in
The main symptom is pruritus and at times this can be incapacitating, interfering with daily activity and sleep. Dyspareunia and urinary retention may occur. It can also be asymptomatic, just with scarring and hypopigmentation.
Squamous cell carcinoma can occur within LS genital lesions.
For more information, see OMIM.
L90.0 – Lichen sclerosus et atrophicus
25674000 – Lichen Sclerosus et Atrophicus
- Bowen disease – 4% of patients can have an associated squamous cell carcinoma.
- Chronic radiation dermatitis – Previously radiated in that area.
- Cicatricial pemphigoid – Look for blisters and erosions, scarring, and stricture formation in later stages.
- Extramammary Paget disease – Look for lichenified or verrucous dry to macerated plaques.
- Infiltrative basal cell carcinoma – Look for pearly areas, prominent telangiectasias.
- Lichen planus – Look for white streaks (Wickham's striae).
- Lichen simplex chronicus – Look for lichenification with exaggerated skin markings on glabrous areas of vulva only, often with excoriations.
- Morphea – Look for loss of hair follicles within shiny atrophic plaques.
- Postmenopausal atrophy – Postmenopausal patient with vaginal dryness and atrophy.
- Psoriasis – Look for psoriasis on other body sites.
- Scar – History of trauma
- Vitiligo – Bright white fluorescence on Wood's lamp.
- Bullous pemphigoid