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Lichen sclerosus - Anogenital in
See also in: Overview,External and Internal Eye
Other Resources UpToDate PubMed

Lichen sclerosus - Anogenital in

See also in: Overview,External and Internal Eye
Contributors: Vivian Wong MD, PhD, Kudakwashe K. Maloney MD, MPhil, Belinda Tan MD, PhD, Susan Burgin MD, David Foster MD, Mary Gail Mercurio MD, Lynne Margesson MD
Other Resources UpToDate PubMed

Synopsis

Lichen sclerosus (LS) is the most common chronic vulvar condition. It is characterized by vulvar hypopigmentation and scarring with loss of normal architecture. Onset is typically at 35-45 years of age, but it can be seen in prepubertal children. Genetic and autoimmune factors are thought to contribute to the pathogenesis of LS.

The main symptom is pruritus, and at times, this can be incapacitating, interfering with daily activity and sleep. Dyspareunia and urinary retention may occur. It can also be asymptomatic, just with scarring and hypopigmentation.

Squamous cell carcinoma (SCC) can occur within LS genital lesions. There is a higher risk of SCC in untreated cases.

For more information, see OMIM.

Codes

ICD10CM:
L90.0 – Lichen sclerosus et atrophicus

SNOMEDCT:
25674000 – Lichen sclerosus et atrophicus

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed:08/13/2020
Last Updated:08/13/2020
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Lichen sclerosus - Anogenital in
See also in: Overview,External and Internal Eye
Lichen sclerosus : Eyelids, Glans of penis, Labia majora, Smooth plaque, White color, Inguinal region, Pruritus, Skin atrophy, Hardened skin
Clinical image of Lichen sclerosus
A shiny white plaque in the intergluteal fold.
Copyright © 2021 VisualDx®. All rights reserved.