Lichen simplex chronicus (LSC) is a lichenified, well-demarcated, scaly plaque that is induced by chronic rubbing and/or scratching. Coexisting papules may also be observed (prurigo nodularis), as may excoriations. As these plaques are self-induced, LSC is almost always found on areas that are within hand's reach, most commonly on the back of the head and neck in women and in the genital area in men. LSC is commonly observed in uncontrolled atopic dermatitis and in other dermatoses that have pruritus as a feature (eg, insect bites, scabies). When LSC is observed on relatively normal skin with no obvious underlying cutaneous (or systemic) precipitants, psychological factors are thought to play a significant role.