Neurologic symptoms occur in the majority of patients with SLE at some point during their illness. Symptoms occur due to multiple mechanisms including vasculopathy, vasculitis, and autoantibodies, and may be augmented by other complications of SLE such as metabolic complications, infections, and treatment toxicities.
Lupus cerebritis must be distinguished from other common sequelae of SLE or its treatment, such as ischemia, infection, or uremia. Lupus cerebritis is usually treated with immunosuppression, such as corticosteroids.
M32.19 – Other organ or system involvement in systemic lupus erythematosus
95644001 – Systemic lupus erythematosus encephalitis
Differential Diagnosis & Pitfalls