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Lupus miliaris disseminatus faciei
See also in: External and Internal Eye
Other Resources UpToDate PubMed

Lupus miliaris disseminatus faciei

See also in: External and Internal Eye
Contributors: Nazgol-Sadat Haddadi MD, MPH, Mehdi Rashighi MD, Robert Stavert MD, MBA, Belinda Tan MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Lupus miliaris disseminatus faciei (LMDF), also known as acne agminata and acnitis, is a relatively rare papular eruption of the face. Because of its characteristic granulomatous histology, LMDF was previously thought to be a variant of cutaneous tuberculosis, granulomatous rosacea, or sarcoidosis. However, today many consider it to be a distinct entity. Some authors have proposed use of the term facial idiopathic granulomas with regressive evolution (acronym FIGURE); however, this term has not been widely accepted.

The exact etiology of LMDF is unknown, but the current hypotheses include an inflammatory reaction to pilosebaceous units, injured hair follicles, or Cutibacterium acnes (formerly Propionibacterium acnes). It is also proposed that the activation of the IL-23 / IL-17 axis might be involved in the disease pathogenesis.

LMDF typically affects adolescents and adults of both sexes, although childhood cases and cases in elderly patients have also been reported. Lesions are usually asymptomatic and resolve spontaneously in 1-3 years with pitted scars. The eruption does not have known associations with any systemic diseases.

Codes

ICD10CM:
L93.2 – Other local lupus erythematosus

SNOMEDCT:
200932001 – Lupoid rosacea

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Last Reviewed:05/10/2020
Last Updated:05/10/2020
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Lupus miliaris disseminatus faciei
See also in: External and Internal Eye
A medical illustration showing key findings of Lupus miliaris disseminatus faciei : Smooth papules
Clinical image of Lupus miliaris disseminatus faciei - imageId=175152. Click to open in gallery.  caption: 'Multiple tiny, red-brown papules and pink erythema of the cheek.'
Multiple tiny, red-brown papules and pink erythema of the cheek.
Copyright © 2024 VisualDx®. All rights reserved.