Contents

SynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferences

Information for Patients

View all Images (15)

Lymphogranuloma venereum - Anogenital in
See also in: Overview,Cellulitis DDx
Other Resources UpToDate PubMed

Lymphogranuloma venereum - Anogenital in

See also in: Overview,Cellulitis DDx
Contributors: Paritosh Prasad MD, Lowell A. Goldsmith MD, MPH, Benjamin K. Fisher MD
Other Resources UpToDate PubMed

Synopsis

Lymphogranuloma venereum (LGV) is an uncommon sexually transmitted infection (STI) caused by the obligate intracellular bacteria Chlamydia trachomatis (serovars L1, L2, or L3). It is worldwide in distribution, but more commonly seen in tropical and subtropical countries. It can present with genital ulcerative disease, lymphadenopathy, or proctocolitis. There are also reports of asymptomatic infection.

There are 3 distinct stages in the course of the disease.

Stage 1:
After a 3- to 30-day incubation period, a small, painless papule or pustule develops on the genital area. Most often, it will erode and ulcerate. This lesion is often asymptomatic and heals without scarring within 1 week. Some patients may be unaware of this occurrence.

Stage 2:
The second or inguinal stage begins 2-6 weeks after the primary lesion. It signifies the spread of the organism from the primary lesion into the lymph nodes and presents as inguinal buboes (painful inflammation of the inguinal lymph nodes), which become fluctuant and rupture. Symptoms include general weakness, headache, and weight loss. It is usually during this stage that patients seek medical help.

Stage 3:
The third stage of LGV is elephantiasis of the penis and scrotum. This swelling is caused by fibrosis with occlusion of the lymphatics, which impedes lymphatic return. Genito-anorectal syndrome can also be seen in the third stage, but usually only in men who have sex with men or in women. These patients initially present with proctocolitis, followed by perirectal abscesses, strictures, fistulas, and rectal stenosis.

Codes

ICD10CM:
A55 – Chlamydial lymphogranuloma (venereum)

SNOMEDCT:
186946009 – Lymphogranuloma Venereum

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Reviewed:11/09/2021
Last Updated:07/07/2022
Copyright © 2022 VisualDx®. All rights reserved.
Lymphogranuloma venereum - Anogenital in
See also in: Overview,Cellulitis DDx
A medical illustration showing key findings of Lymphogranuloma venereum (Stage One (Male)) : Pustule, Skin ulcer, Smooth papule, Inguinal region
Clinical image of Lymphogranuloma venereum - imageId=419994. Click to open in gallery.  caption: 'A bubo, appearing as confluent crusted and scarred tumors in the inguinal area.'
A bubo, appearing as confluent crusted and scarred tumors in the inguinal area.
Copyright © 2022 VisualDx®. All rights reserved.