Lymphogranuloma venereum - Anogenital in
See also in: Overview,Cellulitis DDxAlerts and Notices
Synopsis

There are 3 distinct stages in the course of the disease. After a 3- to 30-day incubation period, a small, painless papule or pustule develops that may erode to form an ulceration. This lesion is often asymptomatic and heals without scarring within 1 week. The second, or inguinal, stage begins 2-6 weeks after the primary lesion and consists of painful inflammation of the inguinal and/or femoral lymph nodes.
The third stage of disease in LGV is called the genito-anorectal syndrome. In women in particular, it may present after asymptomatic first and second stages. Patients initially present in the third stage with proctocolitis, followed by perirectal abscesses, strictures, fistulas, and rectal stenosis.
Codes
ICD10CM:A55 – Chlamydial lymphogranuloma (venereum)
SNOMEDCT:
186946009 – Lymphogranuloma Venereum
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Cellulitis / superinfected erosions
- Monkeypox
- Abscess
- Herpes simplex virus (HSV) or herpes zoster
- Chancroid
- Granuloma inguinale
- Carcinoma – squamous cell, basal cell, etc
- Behçet disease
- Syphilis
- Fournier or gas gangrene
- Hidradenitis suppurativa
- Pyoderma gangrenosum
- Ecthyma gangrenosum
- Inflammatory bowel disease – Crohn disease, ulcerative colitis
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Therapy
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References
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Last Reviewed:11/09/2021
Last Updated:07/07/2022
Last Updated:07/07/2022
Lymphogranuloma venereum - Anogenital in
See also in: Overview,Cellulitis DDx