ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferencesView all Images (6)
Male breast cancer
Print
Other Resources UpToDate PubMed

Male breast cancer

Print Images (6)
Contributors: Amirah Khan MD, Michael W. Winter MD, Benjamin L. Mazer MD, MBA, Paritosh Prasad MD
Other Resources UpToDate PubMed

Synopsis

Male breast cancer is a rare malignant tumor of breast tissue affecting male patients. Male breast cancer accounts for < 0.5% of all cancers diagnosed in men and for 1% of all breast cancers in the United States annually. Its incidence increases with age. Risk factors include family history, African descent, increased estrogen levels, gynecomastia, obesity, hepatic dysfunction, radiation exposure, Klinefelter syndrome, testicular disorders, and genetic mutations including BRCA1, BRCA2, CHEK2, and PALB2. However, it should be noted that most men with breast cancer have no identifiable risk factors.

Due to lack of awareness, patients may present at an advanced stage with a unilateral painless breast mass, nipple retraction, redness or scaling of nipple, and axillary lymphadenopathy. The most common male breast cancer is due to invasive ductal carcinoma. Breast cancers in men are also more likely to be positive for estrogen receptor and negative for human epidermal growth factor receptor 2 (HER2).

Diagnostic tests include breast examination, mammography, and biopsy. Treatment is dependent on stage of disease and typically includes removal of breast tissue, radiation therapy, chemotherapy, and hormonal therapy.

For more information, see OMIM.

Codes

ICD10CM:
C50.929 – Malignant neoplasm of unspecified site of unspecified male breast

SNOMEDCT:
372095001 – Malignant neoplasm of male breast

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Reviewed: 03/28/2019
Last Updated: 04/29/2019
Copyright © 2019 VisualDx®. All rights reserved.
Male breast cancer
Print 6 Images
View all Images (6)
(with subscription)
Male breast cancer : Axillary lymphadenopathy, Gynecomastia, Unilateral, Breast mass
Clinical image of Male breast cancer
Copyright © 2019 VisualDx®. All rights reserved.