The most common cause of nephrotic syndrome in children, this glomerular disease is characterized by normal glomerular appearance by light microscopy, no immune complexes on immunofluorescence, and diffuse podocyte foot process effacement on electron microscopy. Minimal change disease can also present in adulthood and is classically very responsive to steroids. The pathophysiology is not clear, but T-cell dysfunction is thought to be a significant factor.
ICD10CM: N05.0 – Unspecified nephritic syndrome with minor glomerular abnormality
SNOMEDCT: 44785005 – Minimal change disease
Drug Reaction Data
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.