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Contents

Synopsis Codes Best Tests Drug Reaction Data References

Minimal change disease

Contents

Synopsis Codes Best Tests Drug Reaction Data References

Other Resources UpToDate PubMed

Alerts and Notices

Minimal change disease

Contributors: Catherine Moore MD

Other Resources UpToDate PubMed

Alerts and Notices

Synopsis

Minimal change disease : Facial edema, Microscopic hematuria, Proteinuria, Weight gain, BP increased

The most common cause of nephrotic syndrome in children, this glomerular disease is characterized by normal glomerular appearance by light microscopy, no immune complexes on immunofluorescence, and diffuse podocyte foot process effacement on electron microscopy. Minimal change disease can also present in adulthood and is classically very responsive to steroids. The pathophysiology is not clear, but T-cell dysfunction is thought to be a significant factor.

Codes

ICD10CM:
N05.0 – Unspecified nephritic syndrome with minor glomerular abnormality

SNOMEDCT:
44785005 – Minimal change disease

Best Tests

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated:02/11/2016

Minimal change disease

A medical illustration showing key findings of Minimal change disease : Facial edema, Microscopic hematuria, Proteinuria, Weight gain, BP increased

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