ContentsSynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyReferencesView all Images (5)
Neurothekeoma
Print
Other Resources UpToDate PubMed

Neurothekeoma

Print Images (5)
Contributors: Gabriela Cobos MD, Belinda Tan MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Neurothekeoma is a rare, benign tumor of unclear etiology; previously a neural derivation was favored, but more recent studies favor a more fibroblastic / fibrohistiocytic origin.

It most commonly presents in the second decade of life and has a female predilection. It typically presents as a firm, pink-tan or red-brown, dome-shaped papule or nodule. Common locations are the head, arms, and shoulder girdles. Neurothekeomas are slow growing and typically asymptomatic but can cause pain with pressure.

Neurothekeomas are often classified histologically into myxoid, cellular, or mixed type. Of note, in the past, nerve sheath myxomas were often included within the myxoid subtype of neurothekeomas. However, recent studies have shown that nerve sheath myxomas are a distinct and separate clinical entity.

Pediatric Patient Considerations:
Neurokethomas can be seen as dermal nodules in infants and children.

Codes

ICD10CM:
D36.10 – Benign neoplasm of peripheral nerves and autonomic nervous system, unspecified

SNOMEDCT:
51836001 – Neurothekeoma

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

  • Nerve sheath myxoma
  • Melanocytic nevus
  • Myxoid cyst – Usually found on the digits.
  • Adnexal neoplasm
  • Dermatofibroma – May "dimple" with lateral compression.
Pediatric Patient Considerations:

Best Tests

Subscription Required

Management Pearls

Subscription Required

Therapy

Subscription Required

References

Subscription Required

Last Reviewed: 11/20/2017
Last Updated: 12/06/2017
Copyright © 2019 VisualDx®. All rights reserved.
Neurothekeoma
Print 5 Images
View all Images (5)
(with subscription)
Neurothekeoma : Face, Smooth nodule, Smooth papule, Upper arm, Shoulders
Clinical image of Neurothekeoma
Copyright © 2019 VisualDx®. All rights reserved.