- Predisposing medications, including cytarabine, mitoxantrone, bleomycin, and other chemotherapy agents, but not limited to this class. Other triggers include acetaminophen, carbamazepine, and granulocyte colony-stimulating factor (G-CSF); this reaction typically occurs 8-10 days after initiation of the drug.
- A paraneoplastic phenomenon, as it has been reported with myeloproliferative and lymphoproliferative malignancy as well as solid organ malignancies (such as osteosarcoma, testicular carcinoma, metastatic breast cancer, and Wilms tumor) without preceding chemotherapy.
- Human immunodeficiency virus (HIV) and Behçet disease.
- Rarely, with bacterial infection (Serratia, Staphylococcus, Enterobacter, and Nocardia).
Neutrophilic eccrine hidradenitis in Adult
L74.8 – Other eccrine sweat disorders
238754005 – Neutrophilic eccrine hidradenitis
Differential Diagnosis & Pitfalls
Drug Reaction Data