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Nevus of Ota - External and Internal Eye
See also in: Overview
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Nevus of Ota - External and Internal Eye

See also in: Overview
Contributors: William M. Lin MD, Susan Burgin MD, Belinda Tan MD, PhD, Brandon D. Ayres MD, Christopher Rapuano MD, Harvey A. Brown MD, Sunir J. Garg MD, Lauren Patty Daskivich MD, MSHS
Other Resources UpToDate PubMed

Synopsis

Nevus of Ota is unilateral benign dermal melanocytosis that presents as a darkly pigmented patch located in the ophthalmic and maxillary (first and second) trigeminal nerve distribution. It may involve ocular or mucosal surfaces, and can occur bilaterally.

Dermal melanocytoses are caused by an increased number of dermal dendritic melanocytes and can be congenital or acquired. All dermal melanocytoses are more often seen in patients of Asian or African descent, and nevus of Ota, in particular, is more common among females. Nevus of Ota usually occurs in early infancy and early adolescence. It may be present at birth. Unlike the more common congenital dermal melanocytosis, it does not spontaneously regress and may darken or grow in size with puberty. These changes are thought to be secondary to UV radiation and hormonal influences. Malignant transformation is very rare. There is an association with ipsilateral glaucoma in 10% of patients with a nevus of Ota later in life. Rarely, in extensive nevus of Ota, melanocytoma or melanoma has occurred.

Related topic: Choroidal melanoma

Codes

ICD10CM:
D22.39 – Melanocytic nevi of other parts of face

SNOMEDCT:
254817005 – Nevus of Ota

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Differential Diagnosis & Pitfalls

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Therapy

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Last Updated:06/10/2019
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Nevus of Ota - External and Internal Eye
See also in: Overview
Nevus of Ota : Blue color, Bulbar conjunctiva pigmented macule, Face, Hyperpigmented patch, Unilateral distribution
Clinical image of Nevus of Ota
A large dark gray patch on the forehead and temple, extending into the scalp.
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