L20.89 – Other atopic dermatitis
237463009 – Eczema of nipple
Differential Diagnosis & Pitfalls
- Consider Paget disease if there is a unilateral plaque, especially in a middle-aged to older woman.
- If nipple discharge is co-existent, consider intraductal papillary carcinoma.
- Consider an occult contact allergy, such as to preservatives or fragrances, as a cause.
- Erosive adenomatosis of the nipple may present with discharge, a crusted or eroded plaque, or nodularity.
- Benign Toker cell hyperplasia is an extremely unusual condition where normal Toker cells of the breast tissue, particularly of supernumerary nipple, are hyperplastic but lack the malignant qualities of mammary Paget disease.
- Squamous cell carcinoma in situ may assume an eczematous-appearing plaque of the nipple and periareolar skin, but the condition is derived from malignant keratinocytes.
- Hyperkeratosis of the nipple and areola
- Clear cell acanthoma
- Seborrheic keratosis