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Nonbullous impetigo in Infant/Neonate
Other Resources UpToDate PubMed

Nonbullous impetigo in Infant/Neonate

Contributors: Molly Plovanich MD, Catherine J. Wang, Susan Burgin MD
Other Resources UpToDate PubMed


Impetigo is the most common skin infection seen in neonates, with impetiginous infection of atopic dermatitis being the second most common. Caused by Staphylococcus aureus or Group A streptococcus (Streptococcus pyogenes), it is localized to the subcorneal portion of the epidermis. It has been suggested but not proven that males develop impetigo more so in the diaper area and lower abdomen while females may have it on the face more often. Constitutional symptoms and fever are minimal. Minor trauma such as insect bites or abrasions can predispose to infection.

Although methicillin-resistant S. aureus (MRSA) infection of the skin usually presents as recurrent furunculosis or skin abscesses, MRSA has been shown to cause impetigo. Culture and sensitivities should always be performed in patients with lesions suspicious for cutaneous infection, and empiric coverage for MRSA should be instituted if clinical suspicion is high.


L01.01 – Non-bullous impetigo

238374001 – Non-bullous impetigo

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Differential Diagnosis & Pitfalls

A diagnosis of non-bullous impetigo is often mistakenly disregarded due to the lack of inflammation or induration.
  • Arthropod bite or sting
  • Allergic contact dermatitis
  • Pediculosis capitis
  • Seborrheic dermatitis
  • Scabies
  • Psoriasis
  • Tinea capitis
  • Tinea corporis
  • Poison ivy, oak, sumac dermatitis
  • Herpes simplex virus (HSV)
  • Burns (see Thermal or electrical burn, Burn marks of child abuse)
  • Drug eruption general overview
  • Varicella
  • Subcorneal pustular dermatosis
  • Pemphigus foliaceus

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Last Reviewed:07/27/2017
Last Updated:06/14/2018
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Patient Information for Nonbullous impetigo in Infant/Neonate
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Nonbullous impetigo in Infant/Neonate
A medical illustration showing key findings of Nonbullous impetigo : Skin erosion, Yellow color
Clinical image of Nonbullous impetigo - imageId=277147. Click to open in gallery.  caption: 'Numerous discrete and confluent, honey-colored crusts, some hemorrhagic crusts, and surrounding erythema on and around the lips.'
Numerous discrete and confluent, honey-colored crusts, some hemorrhagic crusts, and surrounding erythema on and around the lips.
Copyright © 2024 VisualDx®. All rights reserved.