Omsk hemorrhagic fever - Chem-Bio-Rad Suspicion
Incubation is typically 2-9 days. Initial presentation includes sudden onset of flu-like symptoms with fever, chills, headache, myalgia, arthralgia, and severe prostration. Other hallmarks are flushing of the upper body, conjunctival redness, vesicles on the soft palate, petechiae, cervical lymphadenopathy, and bradycardia. Within 2 weeks, pneumonia, CNS involvement (delirium, seizures, coma), or GI and mucosal bleeding may ensue.
Thrombocytopenia, increased LFTs, and leukopenia may be observed.
Person-to-person transmission has not been documented, but contraction via exposure to infected body fluids has been documented. A vaccine (inactivated TBE) is available only in Russia.
A98.1 – Omsk hemorrhagic fever
48113006 – Omsk hemorrhagic fever
Differential Diagnosis & Pitfalls
- Dengue fever
- Marburg virus
- Hantavirus hemorrhagic fever with renal syndrome
- Rift Valley fever
- Rocky Mountain spotted fever
- Bubonic plague
- Typhoid fever
- Crimean-Congo hemorrhagic fever
- Viral hemorrhagic fever, other
- Other rickettsial infection
- Kyasanur Forest disease
- Yellow fever