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Emergency: requires immediate attention
Omsk hemorrhagic fever - Chem-Bio-Rad Suspicion
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Emergency: requires immediate attention

Omsk hemorrhagic fever - Chem-Bio-Rad Suspicion

See also in: Overview
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Contributors: William R. Dennis MD, MPH, Edith Lederman MD, Noah Craft MD, PhD
Other Resources UpToDate PubMed

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Synopsis

Omsk hemorrhagic fever : Cervical lymphadenopathy, Cough, Fever, Flushing, Headache, Arthralgia, Myalgia, Muskrat exposure
Omsk hemorrhagic fever is an encephalitis of the Flaviviridae family endemic to Russia, specifically the Omsk region and other areas of western Siberia. It is related to yellow fever and Kyasanur forest disease. Tick-borne transmission occurs with exposure to a carrier species (Dermacentor reticulatus, Dermacentor marginatus, Ixodes persulcatus [taiga tick]), but illness may also be contracted via infected water voles and muskrats. Workers handling live animals or animal pelts are at significant risk, as most cases occur in muskrat trappers. Infection confers immunity. The mortality rate of Omsk hemorrhagic fever is 10%.

Incubation is typically 2-9 days. Initial presentation includes sudden onset of flu-like symptoms with fever, chills, headache, myalgia, arthralgia, and severe prostration. Other hallmarks are flushing of the upper body, conjunctival redness, vesicles on the soft palate, petechiae, cervical lymphadenopathy, and bradycardia. Within 2 weeks, pneumonia, CNS involvement (delirium, seizures, coma), or GI and mucosal bleeding may ensue.

Thrombocytopenia, increased LFTs, and leukopenia may be observed.

Person-to-person transmission has not been documented, but contraction via exposure to infected body fluids has been documented. A vaccine (inactivated TBE) is available only in Russia.

Codes

ICD10CM:
A98.1 – Omsk hemorrhagic fever

SNOMEDCT:
48113006 – Omsk hemorrhagic fever

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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References

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Last Updated:12/08/2021
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Emergency: requires immediate attention
Omsk hemorrhagic fever - Chem-Bio-Rad Suspicion
See also in: Overview
Print  
A medical illustration showing key findings of Omsk hemorrhagic fever : Cervical lymphadenopathy, Cough, Fever, Flushing, Headache, Arthralgia, Myalgia, Muskrat exposure
Copyright © 2023 VisualDx®. All rights reserved.