Codes

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

• Verruca vulgaris – Often arises in children where multiple skin lesions, usually affecting the face or fingers, are noted in addition to one or more oral lesions.
• Condyloma acuminatum – Condyloma is considered a sexually transmitted disease caused by one of several strains of HPV, with lesions developing at the site of sexual contact. They are usually sessile, pink, have blunted projections, are larger than papillomas, and often are multiple.
• Verruciform xanthoma – An uncommon benign lesion is typically seen on the gingiva or alveolar mucosa and may have a yellowish tinge.
• Focal epithelial hyperplasia – HPV-related condition that occurs as multiple flattened or rounded papules, typically with the same color as the surrounding mucosa. More common in children, particularly indigenous populations. Focal epithelial hyperplasia-like lesions have also been described in HIV-infected patients.
• Fibroma

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References

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