Paget disease of bone
Alerts and Notices
Synopsis
The disease is often asymptomatic but can cause bone pain, fractures, bone deformity, and symptoms due to compression of surrounding structures (eg, hearing loss, lumbar radicular pain). Genetics and viruses are suspected to play a role in causing the disease.
Bisphosphonates are used to treat the disease.
Codes
ICD10CM:M88.9 – Osteitis deformans of unspecified bone
SNOMEDCT:
2089002 – Osteitis deformans
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Osteoarthritis
- Osteoporosis
- Malignancy (particularly metastasis to bone, primary bone, multiple myeloma)
- Renal osteodystrophy
- Fibrous dysplasia
- Hyperparathyroidism
- Fibrogenesis imperfecta ossium
- Hyperthyroidism
- Hypercalcemia
- Gaucher disease
Best Tests
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Management Pearls
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Therapy
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References
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Last Reviewed: 02/07/2019
Last Updated: 02/25/2019
Last Updated: 02/25/2019
Paget disease of bone
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