Alerts and Notices
SynopsisParotitis is sialadenitis of one or both parotid glands, and is most commonly acute but can also be seen as chronic condition. Characteristic findings include swelling in area of angle of the mandible with erythema and tenderness. Other signs and symptoms include drooling, jaw / neck pain, fever, fatigue, and lymphadenopathy.
Predisposing factors include diabetes or other immunocompromise, recent surgery, poor oral hygiene, poor oral intake, and severe dehydration.
Common etiologies include:
- Bacterial infection, most commonly Staphylococcus aureus and Mycobacterium avium, and viridans streptococci
- Viral infection, eg, paramyxovirus (mumps), Epstein-Barr virus, cytomegalovirus, human immunodeficiency virus
- Autoimmune disease, eg, Sjögren syndrome
- Medications / toxins
- Decreased salivary flow or blockage secondary to poor hydration in elderly patients with reduced oral intake, or postoperative patients, especially after hip and abdominal surgeries
Related topic: suppurative parotitis
K11.20 – Sialoadenitits, unspecified
14756005 – Parotitis
Differential Diagnosis & Pitfalls
- Sjögren syndrome
- Drug-induced xerostomia
- Neoplasm, including Burkitt lymphoma
Drug Reaction DataBelow is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.