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Perioral dermatitis
See also in: External and Internal Eye
Other Resources UpToDate PubMed

Perioral dermatitis

See also in: External and Internal Eye
Contributors: Susan Burgin MD, Noah Craft MD, PhD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed

Synopsis

This summary discusses perioral dermatitis in adults. Perioral dermatitis of childhood is addressed separately.

Perioral dermatitis is a localized inflammatory disorder of uncertain etiology. It manifests as an erythematous papular and pustular eruption involving the nasolabial folds, the upper and lower cutaneous lip, and the chin. The lip margin and the immediate circumoral area are typically spared. Periorbital involvement, predominantly the lower and lateral eyelids, may occur. The term "periorificial dermatitis" is then applied. Fine scaling may be seen. The eruption may be asymptomatic, but burning or itch may be encountered. The granulomatous variant comprises more substantive papules in a similar distribution.

Perioral dermatitis is seen almost exclusively in women aged between 18 and 40. A number of factors have been implicated in causing this condition, such as topical fluorinated glucocorticoids (including inhalers), fluorinated toothpastes, and oral contraceptives.

Codes

ICD10CM:
L71.0 – Perioral dermatitis

SNOMEDCT:
238751002 – Perioral dermatitis

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

  • Differentiate from Rosacea by the perioral distribution.
  • Acne vulgaris
  • Seborrheic dermatitis – scale and erythema predominate; papules and pustules are not a feature.
  • Atopic dermatitis
  • Allergic contact dermatitis
  • Sarcoidosis
  • Lupus miliaris disseminatus faciei
  • Gram-negative folliculitis (see Folliculitis)
  • Demodex folliculitis

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated:07/18/2017
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Patient Information for Perioral dermatitis
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Perioral dermatitis
See also in: External and Internal Eye
A medical illustration showing key findings of Perioral dermatitis : Chin, Erythema, Inferior eyelid, Lateral canthus, Lips, Perioral, Smooth papules, Cheeks
Clinical image of Perioral dermatitis - imageId=326179. Click to open in gallery.  caption: 'Multiple tiny erythematous papules coalescing to form a plaque, with minimal scale at the oral commissure. Note the sparing of the lip margin.'
Multiple tiny erythematous papules coalescing to form a plaque, with minimal scale at the oral commissure. Note the sparing of the lip margin.
Copyright © 2024 VisualDx®. All rights reserved.