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Perioral dermatitis
See also in: External and Internal Eye
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Perioral dermatitis

See also in: External and Internal Eye
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Contributors: Susan Burgin MD, Noah Craft MD, PhD, Lowell A. Goldsmith MD, MPH
Other Resources UpToDate PubMed

Synopsis

This summary discusses perioral dermatitis in adults. Perioral dermatitis of childhood is addressed separately.

Perioral dermatitis is a localized inflammatory disorder of uncertain etiology. It manifests as an erythematous papular and pustular eruption involving the nasolabial folds, the upper and lower cutaneous lip, and the chin. The lip margin and the immediate circumoral area are typically spared. Periorbital involvement, predominantly the lower and lateral eyelids, may occur. The term "periorificial dermatitis" is then applied. Fine scaling may be seen. The eruption may be asymptomatic, but burning or itch may be encountered. The granulomatous variant comprises more substantive papules in a similar distribution.

Perioral dermatitis is seen almost exclusively in women aged between 18 and 40. A number of factors have been implicated in causing this condition, such as topical fluorinated glucocorticoids (including inhalers), fluorinated toothpastes, and oral contraceptives.

Codes

ICD10CM:
L71.0 – Perioral dermatitis

SNOMEDCT:
238751002 – Perioral dermatitis

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated: 07/19/2017
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Perioral dermatitis
See also in: External and Internal Eye
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Perioral dermatitis : Chin, Erythema, Inferior eyelid, Lateral canthus, Lips, Perioral, Smooth papules, Cheeks
Clinical image of Perioral dermatitis
Multiple tiny erythematous papules coalescing to form a plaque, with minimal scale at the oral commissure. Note the sparing of the lip margin.
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