Perioral dermatitis is a localized inflammatory disorder of uncertain etiology. It manifests as an erythematous papular and pustular eruption involving the nasolabial folds, the upper and lower cutaneous lip, and the chin. The lip margin and the immediate circumoral area are typically spared. Periorbital involvement, predominantly the lower and lateral eyelids, may occur. The term "periorificial dermatitis" is then applied. Fine scaling may be seen. The eruption may be asymptomatic, but burning or itch may be encountered. The granulomatous variant comprises more substantive papules in a similar distribution.
Perioral dermatitis is seen almost exclusively in women aged between 18 and 40. A number of factors have been implicated in causing this condition, such as topical fluorinated glucocorticoids (including inhalers), fluorinated toothpastes, and oral contraceptives.
L71.0 – Perioral dermatitis
238751002 – Perioral dermatitis
Differential Diagnosis & Pitfalls
- Differentiate from rosacea by the perioral distribution.
- Acne vulgaris
- Seborrheic dermatitis – scale and erythema predominate; papules and pustules are not a feature.
- Atopic dermatitis
- Contact dermatitis
- Lupus miliaris disseminatus faciei
- Gram-negative folliculitis (see folliculitis)
- Demodex folliculitis
Drug Reaction Data