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Polymorphic eruption of pregnancy
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Polymorphic eruption of pregnancy

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Contributors: Vivian Wong MD, PhD, Susan Burgin MD
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Synopsis

Polymorphic eruption of pregnancy (PEP), or pruritic urticarial papules and plaques of pregnancy (PUPPP), is the most common specific eruption of pregnancy. The etiology is unknown, but it may be related to skin distension. It is a benign condition that almost always begins in the third trimester of a first pregnancy or in the immediate postpartum period. The lesions are associated with striae gravidarum (striae distensae). Pruritus can be severe, leading to sleep disturbance. PEP is associated with a higher frequency of multiple gestation and significant intrapartum weight gain (with a higher degree of stretching of abdominal skin). It is important to note that there is no association with adverse fetal or maternal outcomes. The diagnosis is self-limiting and typically resolves within 2 weeks postpartum. Recurrence with subsequent pregnancies is uncommon.

Codes

ICD10CM:
O26.86 – Pruritic urticarial papules and plaques of pregnancy (PUPPP)

SNOMEDCT:
88697005 – Pruritic urticarial papules and plaques of pregnancy

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Last Reviewed: 03/08/2017
Last Updated: 03/31/2017
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Polymorphic eruption of pregnancy
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Polymorphic eruption of pregnancy : Abdomen, Pruritus, Striae, Maculopapular erythema
Clinical image of Polymorphic eruption of pregnancy
A close-up of urticarial plaques arising within striae.

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