SynopsisCodesDifferential Diagnosis & PitfallsBest TestsReferences
Pulmonic regurgitation
Other Resources UpToDate PubMed

Pulmonic regurgitation

Contributors: Ryan Hoefen MD, PhD
Other Resources UpToDate PubMed


Pulmonic regurgitation refers to dysfunction of the pulmonary valve characterized by incomplete valve closure resulting in diastolic flow of blood from the pulmonary artery to the right ventricle. Causes include endocarditis, rheumatic heart disease, and carcinoid disease, as well as conditions that result in sufficient pulmonary artery dilatation to preclude proper coaptation of the pulmonic valve cusps. Congenital pulmonic regurgitation is rare, although iatrogenic pulmonic regurgitation is commonly seen among patients with congenital right ventricular outflow obstruction, such as in tetralogy of Fallot, who undergo balloon pulmonic valvuloplasty. Patients are generally asymptomatic unless the degree of regurgitation is severe and leads to volume overload and failure of the right ventricle, in which case exertional dyspnea, palpitations, edema, and hepatic congestion may occur.


I37.1 – Nonrheumatic pulmonary valve insufficiency

91434003 – Pulmonic valve regurgitation

Differential Diagnosis & Pitfalls

  • Tricuspid regurgitation
  • Atrial septal defect
  • Ventricular septal defect
  • Marfan syndrome
  • Rheumatic fever and heart disease
  • Carcinoid syndrome
  • Aortic regurgitation
  • Infective endocarditis (eg, Acute bacterial endocarditis, Subacute bacterial endocarditis)
  • Pulmonary hypertension
  • Arrhythmogenic right ventricular cardiomyopathy
  • Constrictive Pericarditis
  • Restrictive cardiomyopathy

Best Tests

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Last Updated:05/30/2023
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Pulmonic regurgitation
A medical illustration showing key findings of Pulmonic regurgitation : Fatigue, Heart murmur, Dyspnea
Copyright © 2024 VisualDx®. All rights reserved.