SynopsisCodesDifferential Diagnosis & PitfallsBest TestsDrug Reaction DataReferences
Renal vein thrombosis
Other Resources UpToDate PubMed

Renal vein thrombosis

Contributors: Benjamin L. Mazer MD, MBA, Catherine Moore MD
Other Resources UpToDate PubMed


Thrombus in the renal veins. A rare cause of renal injury. Most often this develops insidiously with pulmonary embolism being the most common presenting feature. It can also present with decreased renal function, hematuria, proteinuria, and flank pain.

Renal vein thrombosis has many causes, including nephrotic syndrome, hypercoagulable disorders, malignancy, compression from a retroperitoneal mass, trauma, or complication of a renal transplant. In children, it is often secondary to dehydration or sepsis.

Renal vein thrombosis can be unilateral or bilateral. If unilateral, thrombosis more commonly occurs on the left side. Renal vein thrombosis is typically treated with anticoagulation.


I82.3 – Embolism and thrombosis of renal vein

15842009 – Thrombosis of renal vein

Differential Diagnosis & Pitfalls

Differential diagnoses – causes / risk factors of renal vein thrombosis:
  • Nephrotic syndrome - most commonly Membranous nephropathy, membranous lupus nephritis (see Systemic lupus erythematosus), Focal segmental glomerulosclerosis
  • Renal cell carcinoma
  • Renal transplantation
  • Antiphospholipid antibody syndrome
  • Behçet syndrome
  • Acute Pyelonephritis

Best Tests

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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Last Updated:07/12/2016
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Renal vein thrombosis
A medical illustration showing key findings of Renal vein thrombosis : Fever, Flank pain, Nausea, Vomiting, Microscopic hematuria, Proteinuria, Nephromegaly, Gross hematuria, PLT decreased
Copyright © 2024 VisualDx®. All rights reserved.