Reticulate acropigmentation of Kitamura
Alerts and Notices
Synopsis
RAPK was first described in the Japanese population, and it has since been documented in many ethnic groups around the world. RAPK is seen more commonly in females than in males.
RAPK is caused by a mutation in the ADAM10 gene on chromosome 15q21.
Codes
ICD10CM:L81.8 – Other specified disorders of pigmentation
SNOMEDCT:
239133004 – Reticulate acropigmentation of Kitamura
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Dowling-Degos disease (DDD)
- Reticulate acropigmentation of Dohi – Hyperpigmented and hypopigmented macules; predominantly males will be affected.
- Dyschromatosis universalis hereditaria (DUH) – Hyperpigmented and hypopigmented macules diffusely present over trunk; autosomal dominant.
- Xeroderma pigmentosum
- Naegeli-Franceschetti-Jadassohn syndrome (NFJS)
- Dyskeratosis congenita
- Dermatopathia pigmentosa reticularis (DPR)
- Ephelides
- Familial progressive hyperpigmentation – This will be present at birth or soon after. Hyperpigmented patches of varying sizes occur on skin and mucous membranes.
- Cole syndrome
Best Tests
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Management Pearls
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Therapy
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References
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Last Reviewed:08/07/2018
Last Updated:01/23/2022
Last Updated:01/23/2022
Reticulate acropigmentation of Kitamura