The disease is characterized by three stages: rhinitic, infiltrative, and nodular stages. The rhinitic or catarrhal stage is characterized by rhinorrhea and nasal obstruction. The discharge is typically fetid and purulent. The infiltrative or granulomatous stage is characterized by granulomatous papules and nodules in the nose and oropharynx. The nodular stage is characterized by deformity of the nose, with both fibrous and sclerotic lesions prevailing. The later aspects of this stage are sometimes referred to as a sclerotic or fibrotic stage. The entire process occurs over months to years. Usually, systemic symptoms are not seen, but chronic headache may be associated. Some evidence of intrafamilial transmission has been reported in close living quarters.
A48.8 – Other specified bacterial diseases
72409005 – Rhinoscleroma
Differential Diagnosis & Pitfalls