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Rosacea - External and Internal Eye
See also in: Overview,Cellulitis DDx
Other Resources UpToDate PubMed

Rosacea - External and Internal Eye

See also in: Overview,Cellulitis DDx
Contributors: Lauren Strazzula MD, Brandon D. Ayres MD, Christopher Rapuano MD, Sunir J. Garg MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Rosacea is a common, chronic inflammatory condition with a relapsing-remitting course. It presents with facial flushing and localized erythema, telangiectases, papules, and pustules on the nose, cheeks, brow, and chin. It commonly develops in individuals between the ages of 30 and 50.

The etiology of rosacea is poorly understood. Cutaneous vascular changes, inappropriate activation of the immune system, UV and microbial exposure (ie, Demodex mites), and disruption of the epidermal barrier have all been implicated as playing a role in the pathogenesis in this condition. There have been reports of familial rosacea, so an underlying genetic predisposition has not been ruled out.

Rosacea primarily affects individuals with lighter skin phototypes, and females tend to present at a younger age than males. The disease is reported less commonly in skin types IV-VI, perhaps because darker skin types are less prone to photodamage, and flushing and telangiectasias are harder to visualize.

There are 4 main subtypes of the disease: erythematotelangiectatic, papulopustular, phymatous, and ocular rosacea.

Ocular rosacea presents with conjunctivitis, blepharitis, and hyperemia. Patients complain of dry, irritated, itchy eyes. Keratitis, scleritis, and iritis are potential but infrequent complications. Ocular rosacea can occur in patients with or without cutaneous findings.

A rare consequence of chronic rosacea and certain other facial disorders is solid facial edema, sometimes called Morbihan disease.

Since rosacea manifests on the face, it is important to recognize that this disease can have psychosocial consequences, which may affect quality of life.

Codes

ICD10CM:
L71.9 – Rosacea, unspecified

SNOMEDCT:
398909004 – Rosacea

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Eye changes:
Papulopustular rosacea:
Erythematotelangiectatic rosacea:
Flushing:

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Reviewed:03/12/2019
Last Updated:03/21/2019
Copyright © 2021 VisualDx®. All rights reserved.
Rosacea - External and Internal Eye
See also in: Overview,Cellulitis DDx
Rosacea : Erythema, Face, Nose, Telangiectasia, Cheeks
Clinical image of Rosacea
Erythema, telangiectasias, and few scattered inflammatory papules on the cheek.
Copyright © 2021 VisualDx®. All rights reserved.